Organization of the Smallest Eukaryotic Spindle

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چکیده

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Organization of the Smallest Eukaryotic Spindle

In metazoans, plants, and fungi, the spindle checkpoint delays mitosis until each chromosome is attached to one or more of its own kinetochore microtubules (kMTs). Some unicellular eukaryotes, however, have been reported to have fewer kMTs than chromosomes [1-5]. If this is the case, it is unclear how the spindle checkpoint could be satisfied. In the vast majority of the previous studies, mitot...

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ژورنال

عنوان ژورنال: Current Biology

سال: 2011

ISSN: 0960-9822

DOI: 10.1016/j.cub.2011.08.021